Hemophilia Disease is a Common Hereditary Bleeding Disorders all Around The World
Hemophilia is a hereditary bleeding disorder/disease that usually influences males. The number of affected persons worldwide is estimated to be about 600,000. Hemophilia A is more common than hemophilia B, representing 80-85% of the total. A person with hemophilia has low or non-existent degrees of blood clotting protein known as factoring. Coagulation element is important for the clotting mechanism in our bodies to work. There are thirteen blood clotting proteins (coagulation component) in conjunction with platelets and fibrin essential for clotting blood. These thirteen blood clotting proteins commonly combine to shape a clot. If one aspect is lacking or present at low levels, this causes blood clotting problems and a proper clot will now not shape.
Three Common Types of Hemophilia:
Hemophilia A: Hemophilia A is caused by a deficiency of coagulation factor VIII (FVIII). This individual has low ranges or is lacking of Factor VIII, 80% of human beings with hemophilia have this kind of disease. Factor VIII deficiency normally only manifests in males.
Hemophilia B: Hemophilia B is caused by a deficiency of coagulation factor IX (FIX) related to mutations of the clotting factor gene. This individual has low ranges of or is missing absolutely issue IX, 20% of humans with hemophilia have kind B hemophilia. Factor IX deficiency generally handiest manifests in men.
Hemophilia C: This Type has a low range of or is missing absolutely thing XI “Also called FXI or factor XI deficiency” hemophilia C is ten instances rarer than Hemophilia A. Factor XI deficiency is exceptional due to the fact it can show up in each males and females.
The life expectancy of people born with hemophilia, who have access to sufficient treatment, should approach normal with currently available treatment.